The Center for Human Phenomic Scienc (CHPS) has two main locations as well as satellite locations. The protocols cover a wide variety of research areas including: HIV, sleep disorders, cholesterol, obesity, diabetes, various cancers, arthritis, hypertension, renal disease, short bowel syndrome, and neonatal and surgical studies as well as new treatments for various diseases. The CHPSs service over 1200 inpatients and over 6000 outpatients a year. Research subjects range from premature infants to the elderly, with the majority of adults being seen at HUP.
HUP Unit - Dulles Building:
• 8 bed inpatient
• 8 chair and 2 bed outpatient unit
• metabolic kitchen
• Scatterbed nursing services throughout hospital units including the ICUs, ED and operating rooms
UPPMC Unit – 1st Fl Mutch Building:
• 18 outpatient treatment beds
• metabolic kitchen
• 4 bed inpatient unit – 5 West Main
• outpatient unit with 2 treatment rooms, 4 treatment chairs and a consultation room - Main 7
• Scatterbed nursing services in Newborn Nursery - Ravdin Building
The nurse manager should be contacted prior to submitting a new protocol submission to the CHPS and discussions should continue throughout the start-up process.
• Stores 50 ECG Records
• Manual or automatic 3-, 4-, 6-, and 12-lead ECG printouts
• Standard with wired Ethernet, wireless 802.11, and Bluetooth; complies with FAA requirements
• Bi-directional communication with our HeartCentrix connectivity software
• AccuPrint feature restricts ECG printing if lead wires are not properly attached
• Option to use the University of Glasgow ECG interpretation algorithm"
"Most people are used to stepping on a scale at every visit to a doctor's examining room. But monitoring weight – while helpful – is at best a crude and imprecise way to assess a patient’s health. Today's body composition measurement tools provide far more complete and precise information that can help support diagnoses and guide treatment, and can even help athletes make decisions on the training regimens they use to achieve the best performance.
Body composition measurement with DXA can look beyond weight and traditional body mass index (BMI) to determine body fat distribution – an important risk factor in a variety of serious diseases."
This room can be used for trials involving therapeutics, including aerosols. The negative pressure ensures that therapeutics are contained within the room during and after administration.
The Philips telemetry system includes central surveillance capability and portable units.
Body composition measurements are carried out by facility staff at the UPPMC Unit.
Frequent blood sampling and drug level testing
Metabolic testing services include :
• oral glucose tolerance tests
• IV glucose tolerance tests
• mixed meal tolerance tests
• euglycemic clamp
• hypoglycemic clamp
• glucose potentiated arginine test
• 72 hour fasts
Certified nurses and technicians provide a wide range of protocol-driven support services for outpatient studies, including:
• effective implementation of IRB approved protocols
• preparation of nursing instruction sheets
• preparation of laboratory instruction sheets
• measurements of vital signs
• drug screens
• height and weight measurements
• patient monitoring during stress-tests
This is a locked facility with carded access and security monitors.
The facility has the following:
• 2 exam rooms equipped for BP, ECG, height/weight measurements
• 16 outpatient beds, each equipped with a TV
• 6 bedrooms
• 4 outpatient chairs
• waiting room
• private consent room
• bathrooms with showers
• physical therapy room
Services include physicals, monitoring of vital signs, EKG, telemetry, and adminstration of medications (IV, oral, subcutaneous, intramuscular injections).
A pharmacy laboratory space is available within the Penn Presbyterian Medical Center Research Nurse Core.
The core has a fully equipped temperature-controlled laboratory (temperature controlled centrifuges, refrigerators, freezers, de-ionized water and biospecimen laminar flow hood). This protocol-driven service includes processing of bodily fluids, such as blood, saliva, urine, and stool.
The core has -20ºC freezers, and -80ºC freezers for specimen storage. Investigators can store specimens until a full batch has been collected for analysis.
Services include conscious sedation and monitoring of subjects receiving bone marrow biopsies (adults only).
T-cell infusions can be carried out in the core.